Table 1B. Top diseases and functions affected by ERβ5 from analysis of RNA-seq data.
| Score | Focus molecules | Top diseases and functions | |
|---|---|---|---|
| 26 | 35 | Embryonic Development, Nervous System Development and Function, Organ Development | |
| 26 | 35 | Connective Tissue Disorders, Developmental Disorder, Endocrine System Disorders | |
| 24 | 34 | Organismal Injury and Abnormalities, Cell Cycle, Cellular Response to Therapeutics | |
| 24 | 34 | Cardiac Arteriopathy, Cardiovascular Disease, Organismal Injury and Abnormalities | |
| 24 | 34 | Tissue Development, Endocrine System Development and Function, Small Molecule Biochemistry | |
| 24 | 34 | Antimicrobial Response, Inflammatory Response, Cell Signaling | |
| 22 | 33 | Skeletal and Muscular System Development and Function, Embryonic Development, Organismal Development | |
| 22 | 33 | Cell Death and Survival, Cellular Development, Connective Tissue Development and Function | |
| 22 | 33 | Cancer, Organismal Injury and Abnormalities, Endocrine System Disorders | |
| 22 | 33 | Cell Cycle, Digestive System Development and Function, Organ Morphology | |
| 22 | 33 | Cardiovascular Disease, Organismal Injury and Abnormalities, Cardiovascular System Development and Function | |
| 20 | 32 | Cellular Movement, Cell Death and Survival, Cancer | |
| 20 | 32 | Infectious Diseases, Hematological Disease, Hematological System Development and Function | |
| 20 | 32 | Cellular Movement, Cellular Development, Connective Tissue Disorders | |
| 20 | 32 | Cellular Movement, Embryonic Development, Hair and Skin Development and Function | |
| 20 | 32 | Cell Death and Survival, Cellular Compromise, Cell Signaling | |
| 20 | 32 | Cellular Movement, Cellular Development, Cellular Growth and Proliferation | |
| 20 | 32 | Cellular Development, Skeletal and Muscular System Development and Function, Tissue Development |
|
| 20 | 32 | Cardiovascular Disease, Cellular Assembly and Organization, Small Molecule Biochemistry | |
| 20 | 32 | Cellular Assembly and Organization, Hematological Disease, Immunological Disease | |
| 20 | 32 | Infectious Diseases, Inflammatory Disease, Organismal Injury and Abnormalities | |
| 19 | 31 | Cardiovascular System Development and Function, Organismal Development, Cellular Movement | |
| 19 | 31 | Connective Tissue Development and Function, Connective Tissue Disorders, Organismal Injury and Abnormalities | |
| 19 | 31 | Cellular Development, Cellular Growth and Proliferation, Connective Tissue Development and Function | |
| 19 | 31 | Cancer, Organismal Injury and Abnormalities, Gastrointestinal Disease | |