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. 2018 Dec 4;9(6):1103–1121. doi: 10.14336/AD.2018.1110

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Copyright: © 2018 Junfen et al.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution and reproduction in any medium provided that the original work is properly attributed.

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Figure 2. — Expression analysis of miR-1292. (A) qRT-PCR analysis of the dynamic expression of miR-1292 during the senescence and osteogenic differentiation of hADSCs. (B) Conservation of miR-1292 in mammals. (C) Expression of miR-1292 was evaluated in mouse tissues and various cell lines (M-osteoblast: hADSC-derived osteoblast) by miRNA-specific qRT-PCR. (D) The correlations between the expression of senescence markers and miR-1292 or bone formation markers and miR-1292 in clinical bone samples were detected by qRT-PCR. The data, normalized to U6, PPIA or GAPDH expression, are presented as the mean ± SD, n = 3.