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Chromatin modifications at super-enhancers and stretch enhancers.
(a) Genome-wide average ChIP-seq profiles for H3K27ac, H3K4me, H3K4me3, and H3K27me3 at super- and stretch enhancers in H1-ESC, GM12878, and K562. (b) Genomic browser screenshot showing super- and stretch enhancers with ChIP-seq signals for H3K27ac, H3K4me1, H3K4me3, P300, and CTCF, and open chromatin (DNaseI), RNA-seq, and conservation at the locus of SOX2 gene in H1-ES cells.
