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. 2018 Oct 11;13(9):910–922. doi: 10.1080/15592294.2018.1514231

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Figure 6. — Cell type-specificity analysis of super, super-stretch and stretch enhancers.

(a) K-means clustering on the histone modification H3K27ac profile at super, super-stretch and stretch enhancers in five ENCODE cell types (GM12878, K562, H1-ES, HepG2, and HUVEC). (b) Transcriptional abundance in units of RPKM of genes associated with H1-ESC and how these genes are expressed in the other nine cell types tested as shown along the axis. (c) GO analysis of super-, super-stretch and stretch enhancers in H1 ES cell type. (d) Venn diagram shows the overlap of genes associated with super, super-stretch and stretch enhancers, and label the known key cell-identity genes in H1 ES, K562, and Islets cells.