Figure 1.

[A] Sera from a subject positive for AS was assayed in duplicate in dilution series using ImmunoCAP for cetuximab, beef extract and milk extract. The demonstrated response represents the value calculated as corrected for the relevant dilution. Dilution studies using sera from three different AS patients using [B] cetuximab and [C] beef extract and reported as FRU. [D] Representative dilution series using sera from subjects sensitized to milk, peanut, cat or dust mite. [E] Spearman rank correlation between estimated representation of dominant allergen in extract and the percentage difference between sIgE values measured in undiluted sera and those calculated from the 1:8 dilution. Results are from sera from EoE (n=17), PA (n=4), and OAS (n=5) patients with sIgE to mite, cat dander, cow’s milk, and peanut extracts, and are grouped by dominant sensitization to Der p 1, Der p 2, Fel d 1, Bos d 4, Bos d 5, Bos d 6, Bos d 8, Ara h 1, Ara h 2 or Ara h 8.