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. 2018 Nov 23;9(92):36457–36473. doi: 10.18632/oncotarget.26355

Figure 2. Human cSCC have a pro-inflammatory and predominantly Th1 immune microenvironment.

Figure 2

(A) Relative mRNA expression was measured by real-time qPCR for SCC (n = 23), perilesional tissues (P SCC) (n = 23), and normal skin (N) (n = 21). Data are presented as min to max box plots of relative mRNA expression. Kruskall-Wallis test with Dunn's Multiple Comparison Test *p < 0.05, **p < 0.01, ***p < 0.001. (B) Correlation between the relative expression of cytokines (OSM, IL-8, and IL-1β) of patient SCC lesions (n = 23). Data are presented as dot plots of relative mRNA expression. Spearman's correlation coefficients (r) are shown. *p < 0.05, **p < 0.01, ***p < 0.001.