Table 2. Immune infiltrates in human cSCC.
Intratumoral | Invasion front | Peritumoral | |
---|---|---|---|
CD3 | 688 (88-2096) | 1483 (142-3828) (**, p<0.01) |
822 (50-3406) |
CD68 | 330 (19-1102) | 534 (143-1006) (*, p<0.05) |
350 (94-770) |
MPO | 108 (0-707) | 158 (14-676) (**, p<0.001) |
66 (2-375) |
Data are presented as the mean (min-max) number of inflammatory cells per field (0.6 mm diameter) determined using assisted-counting software (Visilog Noesis). We compared the cell mean number per field of CD3, CD68 or MPO positive cells in the intratumoral, invasion front, and peritumoral zones for each tumor. Statistical analysis were performed using a Kruskall-Wallis test with Dunn's Multiple Comparison Test *p < 0.05, **p < 0.01, ***p < 0.001.