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Pja2 inhibits Wnt/β-catenin signaling. (A) Pja2 inhibits Wnt 3a-mediated reporter activity. TOP-Flash Wnt reporter construct was transfected with HA-pja2. Reporter activity was analyzed upon treatment with control and Wnt 3a-conditioned media. (B) Pja2 inhibits activator of Wnt signaling-mediated reporter activity. Reporter activity was measured after transfection with the indicated plasmids into HEK293T cells. **p<0.01.
