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. 2018 Dec 7;13(12):e0205144. doi: 10.1371/journal.pone.0205144

Fig 3. Effect of SPS on GR internalization in the vHipp.

Fig 3

A) Cartoon of dissected brain region and representative western of cytoplasmic (cy) and nuclear (nu) vHipp samples. B) SPS had no effect on baseline GR/actin ratios or nGR/cGR internalization ratios (SPS = 12, Con = 13). C) Cy GR/actin were enhanced during FC relative to nu GR/actin ratios. SPS had no effects on GR/actin or nGR/cGR ratios after FC. D) SPS had no effect on normalized GR/actin or nGR/cGR ratios, but both cy and nu GR/actin ratios were enhanced relative to baseline levels. Also, nGR/cGR ratios after FC were decreased relative to baseline. +—significant one-sample t-test. SPS/0’ = 12, SPS/30’ = 8, SPS/60’ = 9; Con/0’ = 11, Con/30’ = 7, Con/60’ = 7.