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. 2018 Nov 27;12(11):e0006903. doi: 10.1371/journal.pntd.0006903

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© 2018 Heffron et al

This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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Fig 2 — DENV serotypes share an average of 41% sequence similarity with the aligned ZIKV NS2B epitope (A). Serum from rhesus macaques infected with ZIKV-FP (animals B1, D1, and D2) or ZIKV-MR766 (C1) was assayed for cross-reactivity against polyproteins of DENV serotypes 1–4 (B-E, respectively). The segment of DENV NS2B which aligns with the ZIKV NS2B_1427-1451RD25 epitope is highlighted in grey.