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. Author manuscript; available in PMC: 2018 Dec 7.
Published in final edited form as: Lab Chip. 2016 Apr 21;16(8):1466–1472. doi: 10.1039/c5lc01173f

Figure 5. Variable responding profiles of human islets in response to secretagogues.

Figure 5

(A) Calcium signalling in response to 25 mM glucose and 30 mM KCI (n = 3, total of 300 islets). (B) Calcium concentration Heat-map in response to 25 mM glucose and 30 mM KCI (n = 3, total of 300 islets). (C) Mitochondrial potential changes in response to 25 mM glucose (n = 3, total of 300 islets). (D) Mitochondrial potential change Heat-map in response to 25 mM glucose (n = 3, total of 300 islets). Information about different response profiles of human and mouse islets in response to varying glucose concentrations and calcium-induced mitochondrial potential oscillation patterns have been presented in the SI Figures.