Table 4.

Annual prevalence of PrEP use (Rx) and new HIV diagnoses (Dx) per 100,000 population and PrEP-to-need ratio (PnR), overall and by gender, age, and region, United States 2012-17

	Year																		EAPC for PnR
	2012			2013			2014			2015			2016			2017
	Rx*	Dxˠ	PnR °	Rx	Dx	PnR	Rx	Dx	PnR	Rx	Dx	PnR	Rx	Dx	PnR	Rx	Dx	PnR
Overall	3.3	16.5	0.2	4.7	16.2	0.3	10.3	16.6	0.6	21.9	14.7	1.5	28.2	14.7	1.9	36.7	14.7	2.5	+61%
Gender
Female	2.9	6.6	0.4	3.9	6.2	0.6	5.2	6.1	0.9	7.1	5.4	1.3	3.7	5.5	0.7	4.3	5.5	0.8	+10%
Male	3.7	27.0	0.1	5.6	26.6	0.2	15.6	27.5	0.6	37.3	24.4	1.5	53.9	24.4	2.2	70.6	24.4	2.9	+72%
Age
24 yr and younger	2.7	18.2	0.1	3.9	17.8	0.2	7.4	18.6	0.4	14.5	16.8	0.9	16.4	16.2	1.0	24.1	16.2	1.5	+55%
25 to 34 yr	6.5	29.9	0.2	9.9	30.0	0.3	22.7	32.1	0.7	50.2	29.5	1.7	66.9	30.8	2.2	89.3	30.8	2.9	+61%
35 to 44 yr	4.9	22.3	0.2	7.0	21.1	0.3	16.7	21.9	0.8	35.5	18.7	1.9	47.2	18.7	2.5	58.5	18.7	3.1	+63%
45 to 54 yr	3.6	18.1	0.2	4.9	17.4	0.3	11.0	16.8	0.7	24.4	14.7	1.7	32.4	14.4	2.3	38.8	14.4	2.7	+63%
55 yr and older	1.1	4.9	0.2	1.3	5.2	0.3	2.4	4.9	0.5	5.0	4.2	1.2	6.4	4.3	1.5	8.6	4.3	2.0	+57%
Region
Midwest	2.1	10.1	0.2	3.2	10.0	0.3	7.7	9.7	0.8	17.5	9.0	1.9	23.5	8.9	2.6	30.1	8.9	3.4	+65%
Northeast	6.0	16.9	0.4	9.2	16.3	0.6	18.3	16.6	1.1	37.6	13.6	2.8	47.4	13.2	3.6	62.3	13.2	4.7	+63%
South	3.0	22.0	0.1	3.6	21.8	0.2	8.2	22.2	0.4	17.6	20.2	0.9	22.6	20.1	1.1	29.8	20.1	1.5	+60%
West	2.9	13.0	0.2	4.5	12.4	0.4	10.2	13.4	0.8	21.6	11.7	1.8	28.1	12.2	2.3	36.0	12.2	3.0	+59%

^*Annual prevalence of PrEP use per 100,000 population

^ˠAnnual incidence of new HIV diagnoses per 100,000 population

^°PrEP-to-need ratio: ratio of the number of PrEP users to the number of people newly diagnosed with HIV by category in corresponding year.

Notes: Overall, and gender and age-specific estimates are calculated for the US 50 states, District of Columbia and Puerto Rico.

Estimates of new HIV diagnoses from year 2016 are used to calculate PrEP-to-need ratios for 2017.