Fig. 1.

Time course of laboratory and radiological results. (A) The 24-hour urinary cortisol and ALT concentrations plotted against time (days). Solid line indicates urinary free cortisol levels. Dashed line indicates ALT levels. (B) Representative cross-sectional CT images at diagnosis (day 0), postadrenalectomy (day 91), and following initiation of pembrolizumab therapy (day 180). White arrowheads indicate the primary tumor at diagnosis and, following treatment, sites of local and metastatic recurrence.