Table 2.
Main Studies Reporting the Effect of Shunt Reduction in Patients with Chronic/Recurrent Refractory Post-TIPS HE.
| Studies | No. with refractory HE/treated with TIPS | Child–Pugh class | No. of pts. improved | Adverse events after TIPS reduction | PPG pre (mmHg) | PPG post (mmHg) |
|---|---|---|---|---|---|---|
| Bureau, 201755 | 1/29 | C:1 | 1 | – | – | – |
| De Santis, 201656 | 2/38 | B:1 C:1 |
2 | Ascites 1 Bleeding 1 |
6.5 ± 2.6 | 12.7 ± 3.8 |
| Nardelli, 201637 | 3/82 | B:1 C:2 |
3 | – | 5.6 ± 3.2 | 12.1 ± 2.7 |
| Cookson, 201157 | 8/NR | B:3 C:5 |
5 | Bleeding 3 Deaths 2 |
4.9 ± 3.6 | 10.5 ± 3.9 |
| Fanelli, 200950 | 12/189 | A:1 B:5 C:6 |
12 | Ascites 1 OLT 1 Deaths 4 |
6.6 ± 2.69 |
15.1 ± 3.4 |
| Riggio, 200834 | 6/78 | 6 | Ascites 1 Death for bleeding 1 |
5.5 ± 2.1 |
14.7 ± 1.9 |
|
| Chung, 200840 | 4/113 | C:4 | 4 | – | – | |
| Maleux, 200748 | 16/266 | A:2 B:13 C:1 |
10 | Ascites 1 Bleeding 1 OLT 1 |
5.25 ± 2.4 |
11 ± 3.1 |
| Kochar, 200639 | 38/733 | 21 | Bleeding 3 Ascites 3 Deaths 3 |
– | – | |
| Kerlan, 199558 | 5/NR | 4 | Bleeding 1 | – | – |