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. 2018 Dec 7;6:219. doi: 10.1186/s40168-018-0607-0

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© The Author(s). 2018

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Isoprene degradation pathway. Enzymes: IsoABCDEF, isoprene monooxygenase; IsoI, glutathione-S-transferase; IsoH, dehydrogenase. HGMB 1-hydroxy-2-glutathionyl-2-methyl-3-butene, GMB 2-glutathionyl-2-methyl-3-butenal, GMBA 2-glutathionyl-2-methyl-3-butenoic acid, SG glutathione, GSH reduced glutathione. The question mark indicates uncertainty in the details of the catabolic pathway from GMBA