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. 2018 Dec 8;18:185. doi: 10.1186/s12871-018-0645-y

Table 1.

Overview of definitions of vasoplegia used and their criteria

Vasodilation criterion Hemodynamic criterion Vasopressor criterion Preload criterion Time moment/period
Argenziano [1] MAP < 70 mmHg CI > 2.5 l·min− 1·m− 2 nor > 8 μg·min− 1 5 min after CPB
Levin [2] MAP < 50 mmHg and SVR < 800 dynes·s·cm− 5 CI > 2.5 l·min− 1·m− 2 any vasopressor CVP < 5 mmHg and PCWP < 10 mmHg first 3 h after ICU arrival
Patarroyo [9] SVR < 800 dynes·s·cm− 5 CI > 2.5 l·min− 1·m− 2 ≥ 2 vasopressors:
1. epi > 4 μg/min,
2. nor ≥4 μg/min,
3. dopa ≥5 μg· kg− 1·min− 1,
4. vasopressin ≥1 U/hr
6–48 h after ICU arrival
Unified definition MAP < 50 mmHg
or SVR < 800 dynes·s·cm− 5
CI > 2.5 l·min− 1·m− 2 nor > 200 ng·kg− 1·min− 1 or equivalent doses of other vasopressors:
epi ≥ 200 ng·kg− 1·min− 1;
dopa ≥30 μg·kg− 1·min− 1; phenyl ≥2 μg·kg− 1·min− 1; or vasopressin ≥0.08 U·min− 1
first 48 h after ICU arrival