Table 2.

Rank correlation p-values for URM (U) and seed target (S) motifs

	Regmex Brownian bridge	Regmex modified rank sum	DRIMust	Sylamer
GCCCGG	1.23e−230*	5.91e−70	3.07e−116	1.20e−34
CCCGGT	1.77e−210*	4.55e−52	8.19e−110	5.95e−27
TGCCCG	9.90e−200*	3.35e−49	1.23e−98	4.13e−50
ATGCCC	6.63e−125*	1.73e−24	2.09e−65	2.89e−42
AATGCC	1.76e−60*	1.90e−10	7.78e−38	1.44e−29
CCGGTa	1.91−45*	1.09e−05	6.55e−31	5.00e−06
CCGGTt	2.80e−17*	0.020	2.58e−15	n.s.
CCGGTg	6.49−11*	n.s.	1.27e−09	n.s.
CCGGTc	1.16e−06	0.0044	1.06e−11*	n.s.
tAATGC	n.s.	n.s.	0.00014*	n.s.
cAATGC	n.s.	n.s.	0.0018*	n.s.

p-value outputs for 6-mer motifs overlapping a 10-mer spiked into a randomly re-ordered gene list for three methods, Regmex, Sylamer and DRIMust. Motif bases overlapping the 10-mer spike-in are in capital

n.s. Not significant

*Most significant method