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. 2018 Dec 1;24:8685–8692. doi: 10.12659/MSM.910955

Figure 4.

Figure 4

LncRNA PVT1 directly interacted with miR-26b. (A) Sequence alignment and schematic diagram of miR-26b with the wild-type (top) and mutated (bottom) 3’UTR of PVT1. (B, C) The luciferase activity of the reporter vectors was detected in HCT116 cells after 48 hours of co-transfection wide type or mutant PVT1-3’UTR with miR-26b respectively; pRL-TK was used for normalization. The data are shown as the mean ±SD of 3 independent experiments. (** P<0.01; *** P<0.001; ns – not significant). LncRNA – long noncoding RNA.