Table 2.

Association Between Longitudinal Walking Speed Change and Knee Structure Change.

BML Change (Decrease/No Change = Reference)
Group	Walking Speed Change	Decrease/No Change	Increase	Adjusted* Odds Ratio
		n (%)	n (%)	OR (95%Cl)
Overall	Slower	35 (58%)	25 (42%)	1.79 (1.00, 3.20)
	Faster/No Change	200 (70%)	86 (30%)	Reference
Accelerated Knee OA	Slower	7 (30%)	16 (70%)	3.04 (1.03, 8.95)
	Faster/No Change	46 (55%)	37 (45%)	Reference
Common Knee OA	Slower	15 (68%)	7 (32%)	1.17 (0.41, 3.32)
	Faster/No Change	72 (73%)	27 (27%)	Reference
No Knee OA	Slower	13 (87%)	2 (13%)	0.60 (0.12, 2.92)
	Faster/No Change	82 (79%)	22 (21%)	Reference
Effusion Change (Decrease/No Change = Reference)
		Decrease/No Change	Increase
		n (%)	n (%)
Overall	Slower	36 (60%)	24 (40%)	1.48 (0.83, 2.66)
	Faster/No Change	195 (68%)	91 (32%)	Reference
Accelerated Knee OA	Slower	6 (26%)	17 (74%)	3.39 (1.10, 10.49)
	Faster/No Change	41 (49%)	42 (51%)	Reference
Common Knee OA	Slower	17 (77%)	5 (23%)	0.57 (0.19, 1.73)
	Faster/No Change	67 (68%)	32 (32%)	Reference
No Knee OA	Slower	13 (87%)	2 (13%)	0.80 (0.16, 4.02)
	Faster/No Change	87 (84%)	17 (16%)	Reference
CDI Change (Increase/No Change = Reference)
		Decrease	Increase/No Change
		n (%)	n (%)
Overall	Slower	18 (30%)	42 (70%)	0.89 (0.48, 1.66)
	Faster/No Change	97 (34%)	189 (66%)	Reference
Accelerated Knee OA	Slower	12 (52%)	11 (48%)	0.81 (0.30, 2.16)
	Faster/No Change	51 (61%)	32 (39%)	Reference
Common Knee OA	Slower	4 (18%)	18 (82%)	0.75 (0.22, 2.55)
	Faster/No Change	22 (22%)	77 (78%)	Reference
No Knee OA	Slower	2 (13%)	13 (87%)	0.49 (0.10, 2.35)
	Faster/No Change	24 (23%)	80 (77%)	Reference

CDI = cartilage damage index, BML = bone marrow lesion, OR = odds ratio, 95% CI = 95% confidence intervals, OA = osteoarthritis,

^*Adjusted for baseline age, body mass index, WOMAC pain, and physical activity