Table 5.

Association Between Longitudinal Walking Speed Change and Knee Structure Change Excluding Individuals with Imputed Missing Structural Data.

BML Change (Decrease/No Change = Reference)
Group	Walking Speed Change	Decrease/No Change	Increase	Adjusted* Odds Ratio
		n (%)	n (%)	OR (95%CI)
Overall	Slower	34 (57%)	26 (43%)	1.95 (1.09, 3.49)
	Faster/No Change	192 (70%)	81 (30%)	Reference
Accelerated Knee OA	Slower	7 (30%)	16 (70%)	3.04 (0.99, 9.30)
	Faster/No Change	39 (54%)	33 (46%)	Reference
Common Knee OA	Slower	14 (64%)	8 (36%)	1.50 (0.54, 4.21)
	Faster/No Change	71 (73%)	26 (27%)	Reference
No Knee OA	Slower	13 (87%)	2 (13%)	0.60 (0.12, 2.92)
	Faster/No Change	82 (79%)	22 (21%)	Reference
Effusion Change (Decrease/No Change = Reference)
		Decrease/No Change	Increase
		n (%)	n (%)
Overall	Slower	37 (62%)	23 (38%)	1.44 (0.80, 2.61)
	Faster/No Change	189 (69%)	84 (31%)	Reference
Accelerated Knee OA	Slower	6 (26%)	17 (74%)	3.59 (1.11, 11.62)
	Faster/No Change	35 (49%)	37 (51%)	Reference
Common Knee OA	Slower	17 (77%)	5 (23%)	0.59 (0.20, 1.79)
	Faster/No Change	66 (68%)	31 (32%)	Reference
No Knee OA	Slower	14 (93%)	1 (7%)	0.40 (0.05, 3.44)
	Faster/No Change	88 (85%)	16 (15%)	Reference
CDI Change (Increase/No Change = Reference)
		Decrease	Increase/No Change
		n (%)	n (%)
Overall	Slower	19 (32%)	41 (68%)	0.98 (0.53, 1.81)
	Faster/No Change	91 (33%)	182 (67%)	Reference
Accelerated Knee OA	Slower	12 (52%)	11 (48%)	0.84 (0.31, 2.30)
	Faster/No Change	45 (63%)	27 (37%)	Reference
Common Knee OA	Slower	5 (23%)	17 (77%)	1.00 (0.32, 3.13)
	Faster/No Change	22 (23%)	75 (77%)	Reference
No Knee OA	Slower	2 (13%)	13 (87%)	0.49 (0.10, 2.35)
	Faster/No Change	24 (23%)	80 (77%)	Reference

CDI = cartilage damage index, BML = bone marrow lesion, OR = odds ratio, 95% CI = 95% confidence intervals, OA = osteoarthritis,

^*Adjusted for baseline age, body mass index, frequent pain, and physical activity