. Author manuscript; available in PMC: 2020 Apr 1.

Published in final edited form as: Arthritis Care Res (Hoboken). 2019 Apr;71(4):521–529. doi: 10.1002/acr.23617

Table 5.

Standardized betas showing associations between changes in PROMIS T-scores and changes in disease activity measures (n = 106)¹

PROMIS Measure	CDAI	Swollen Joints	Tender Joints	Patient Global	Assessor Global
Physical Global Health²	−0.29^**	−0.12	−0.30^**	−0.21^*	−0.24^*
Mental Global Health²	−0.34^**	−0.20	−0.33^**	−0.18	−0.22^*
Pain Intensity 3a²	0.27^*	0.12	0.24^*	0.23^*	0.20
Pain Interference	0.33^**	0.12	0.31^**	0.30^**	0.28^**
Pain Behavior	0.27^*	0.059	0.28^**	0.28^**	0.20
Sleep Disturbance	0.38^***	0.12	0.36^***	0.35^**	0.34^**
Sleep –Related Impairment	0.33^**	0.11	0.34^**	0.27^**	0.30^**
Fatigue	0.33^**	0.086	0.35^**	0.29^**	0.27^*
Anxiety	0.23^*	0.048	0.24^*	0.24^*	0.16
Depression	0.088	−0.039	0.067	0.24^*	0.10

Multivariable models adjusted for study site, gender, race, age, seropositivity, and RA disease duration to predict means by CDAI category and to determine trend across categories.

Standardized betas reflect the amount of standardized deviations a dependent variable changes per standard deviation change in the independent variable.

indicates P ≤ 0.05;

^**

indicates P ≤ 0.01;

^***

indicates P ≤ 0.001.

Global Health and Pain Intensity 3a scores were collected using short forms. All other instruments were collected using computerized adaptive tests. Lower Global Health scores indicate worse global health. For all other measures, high scores indicate worse symptoms. All PROMIS scores range from about 20–80 and are standardized to a general population mean (SD) of 50 (10).