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. Author manuscript; available in PMC: 2019 Apr 18.
Published in final edited form as: Genes Immun. 2018 Jun 8;20(4):261–272. doi: 10.1038/s41435-018-0031-2

FIGURE 4.

FIGURE 4

iNKT cell numbers in the thymus are regulated by the B6.129c3 interval. A). iNKT cell (left), total thymocyte (middle), thymocyte subset (right) numbers were compared between C57BL/6 and B6.129c3 mice. B). No significant difference in the distribution of thymic iNKT subsets between B6 and B6.129c3 mice. iNKT cell subsets were identified based on PLZF and RORγt expression as indicated by colored boxes (left). Cumulative numbers of iNKT cell subsets are shown (right). Data represent the cumulative results of 4 separate experiments using 9 – 13 week old female mice. Mice were age matched in each experiment. Statistical analysis was performed using an unpaired T-test. *p ≤ 0.05, **p ≤ 0.01, ***p ≤ .001