Table 1.

Features related to HCV-SS in comparison to pSS

Higher mean age on diagnosis

Lower frequency of parotidomegaly

Liver involvement in majority of patients

Clinical features of cryoglobulinemia Cutaneous vasculitis Peripheral neuropathy Renal involvement

Immunological patterns Higher frequency of cryoglobulins Higher frequency of RF activity Higher frequency of hypocomplementemia Lower frequency of positive anti-Ro and anti-La antibodies