Costus afer Protects Cardio-, Hepato-, and Reno-Antioxidant Status in Streptozotocin-Intoxicated Wistar Rats

. 2018 Nov 25;2018:4907648. doi: 10.1155/2018/4907648

	SOD (U/min/mg of protein)	CAT (U/min/mg of protein)	GSH ( μ mol/mg of protein)	MDA ( μ mol/mg of protein)
Control	11.66 ± 2.13^a	48.12 ±2.36^a	133.97± 5.46^b	4.68 ± 1.89^a,b
Diabetic Control	28.85 ± 2.95^b	186.67±78.46^c	64.71± 10.59^a	6.86 ± 0.33^b
DHE 250 mg/kg	25.45 ± 2.93^a,b	98.38 ± 4.77^b	69.85 ± 3.33^a	4.65 ± 0.46^a,b
DHE 500 mg/Kg	20.16 ± 1.79^a,b	83.38 ± 2.93^b	87.65 ± 7.04^a,b	3.94 ± 0.16^a
DHE 1000mg/kg	13.95 ± 6.23^a	50.96 ± 4.77^a	125.00±2.89^b	3.09 ± 0.59^a
Met 250 mg/Kg	12.64 ± 1.28^a	50.62 ± 9.04^a	100.74 ±3.33^b	3.08 ± 0.03^a

DHE: diabetic treated with hydroethanolic extract of C. afer; Met: metformin. SOD: superoxide dismutase, CAT: catalase, GSH: reduced glutathione, MDA: Malondialdehyde. Each value represents mean ± S.E.M. (n=6). Means with different letters (a, b, c, and d) within a column are significantly different from each other at p< 0.05.