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. Author manuscript; available in PMC: 2018 Dec 9.
Published in final edited form as: J Biomed Inform. 2017 Jan 25;66:241–247. doi: 10.1016/j.jbi.2017.01.014

Table 2.

Top ranked KEGG pathways containing selected biomarkers from Table 1

Disease Pathway Biomarkers (Gene Names)

Sepsis Cytokine-cytokine receptor interaction - human CCL2, TNFRSF1B, CCL4, IL10, CSF3, IL6, LTA, IL1B
TNF signaling pathway - human CCL2, IL6, LTA, TNFRSF1B, IL1B
Chagas disease (American trypanosomiasis) - human IL10, CCL2, IL1B, IL6
NOD-like receptor signaling pathway - human CCL2, IL6, IL1B, IL8
Cytosolic DNA-sensing pathway - human IL6, IL1B, CCL4