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. 2018 Nov 4;10(11):3136–3147. doi: 10.18632/aging.101616

Table 1. Cardiac function parameters of rats in each group following CME modeling.

Group N LVEF(%) LVFS(%) CO(L/min) LVIDd(mm)
Sham 6 83.96±3.31 53.38±2.47 0.25±0.018 5.83±0.46
CME 6 53.76±4.20a 25.43±1.51a 0.10±0.016a 7.46±0.45a
CME+shRNA 6 74.33±5.49ab 47.84±3.42ab 0.21±0.027ab 6.29±0.38ab
CME+Control 6 52.15±4.17ac 25.77±2.03ac 0.11±0.016ac 7.44±0.54ac
CME+shRNA+3-MA 6 64.11±4.55abc 36.35±2.58abc 0.15±0.023abc 6.92±0.45abc

Abbreviations: CME, coronary microembolization; LVEF, left ventricular ejection fraction; LVFS, left ventricular fractional shortening; CO, cardiac output; LVIDd, left ventricular internal diameter at end-diastole. Data are presented as mean ± SD. aP < 0.05 versus the Sham group; bP < 0.05 versus the CME group; cP < 0.05 versus the CME+shRNA group.