Figure 4.

Severe defects in mitochondrial networks were more frequent and manifested earlier in the ageing process than sarcomere defects or defects in protein homeostasis. Data presented show individual scoring of sarcomere defects at 15°C (A), 20°C (B), and 25°C (C); scoring of mitochondrial network fragmentation at 15°C (D), 20°C (E), and 25°C (F); and protein degradation at 15°C (G), 20°C (H), and 25°C (I). All data represent n = 10.