Table 1. L-BMAA administration prolonged motor-evoked potential (MEP) latency and lowered MEP amplitude.
Time point | Group | Latency (ms) | Wave amplitude (μV) |
2 weeks | Normal | 2.1±0.5** | 3.6±0.21** |
Vehicle | 6.6±0.31 | 0.2±0.16 | |
C+A | 5.35±0.28* | 1.2±0.25** | |
L-ser | 4.26±0.3** | 2.26±0.11** | |
Combined | 4.9±0.55** | 3.7±0.21** | |
4 weeks | Vehicle | 7.1±0.65 | 0.2±0.18 |
C+A | 4.6±0.42** | 3.0±0.78** | |
L-ser | 4.22±0.10** | 2.2±0.42** | |
Combined | 4.19±0.68** | 4.6±0.43** | |
8 weeks | Vehicle | 7.3±0.5 | 0.2±0.08 |
C+A | 2.3±0.12** | 2.0±0.28* | |
L-ser | 4.2±0.9** | 3.67±0.32** | |
Combined | 4.35±0.18** | 4.75±0.55** |
C+A, C16+Ang-1; L-ser, L-serine; combined, C16+Ang-1 and L-serine. Data are expressed as mean±SD, n=5. *p<0.05 and **p<0.01 vs. the vehicle group (one-way ANOVA).