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. 2018 Nov 14;5:40. doi: 10.21037/sci.2018.11.01

Table 2. The effect of stem cell therapy on the insulin daily requirement levels, HbA1C and peptide in different types of diabetes.

Variables Type of diabetes Summary estimates of mean difference 95% CI P value I2 (%) Heterogeneity test
HbA1C (%) T1DM 1.71 (0.51, 2.92) 0.005 94 3,076 (P<0.0001)
T2DM 1.27 (0.84, 1.70) <0.0001 88 68.80 (P<0.0001)
C-peptide (ng/mL) T1DM −0.25 (−0.45, −0.05) 0.01 98 711.18 (P<0.0001)
T2DM −0.13 (−0.96, 0.70) 0.76 99 630.14 (P<0.0001)
Daily insulin requirement (U/kg per day) T1DM 0.07 (−0.07, 0.20) 0.35 99 833.70 (P<0.0001)
T2DM 0.23 (0.03, 0.44) 0.02 93 44 (P<0.0001)