Table 1. Time to treatment initiation UVA cohort: patient demographic, treatment/treatment center, and prognostic characteristics with associated mean and median TTI.
| Category | Number (%) | Mean TTI | Median TTI | P value |
|---|---|---|---|---|
| Total | 12,546 (100.0) | |||
| Race/ethnicity | <0.001 | |||
| Non-Hispanic White | 10,091 (80.4) | 37.7 | 33 | |
| Hispanic | 546 (4.4) | 48.6 | 40 | |
| Non-Hispanic Black | 1,116 (8.9) | 49.8 | 42 | |
| AAPI | 117 (0.9) | 41.8 | 35 | |
| Other/unknown | 676 (5.4) | 36.4 | 32 | |
| Gender | <0.001 | |||
| Male | 3,727 (29.7) | 42.9 | 35 | |
| Female | 8,819 (70.3) | 37.7 | 33 | |
| Year of diagnosis | <0.001 | |||
| 2004 | 641 (5.1) | 34.8 | 30 | |
| 2005 | 656 (5.2) | 37.1 | 32 | |
| 2006 | 739 (5.9) | 36.3 | 31 | |
| 2007 | 905 (7.2) | 39.0 | 33 | |
| 2008 | 943 (7.5) | 38.4 | 33 | |
| 2009 | 1,134 (9.0) | 38.8 | 33 | |
| 2010 | 1,181 (9.4) | 39.9 | 34 | |
| 2011 | 1,324 (10.6) | 40.4 | 34 | |
| 2012 | 1,539 (12.3) | 38.9 | 34 | |
| 2013 | 1,717 (13.7) | 40.8 | 34 | |
| 2014 | 1,767 (14.1) | 41.2 | 35 | |
| Age (years) | 0.177 | |||
| >70 | 2,396 (19.1) | 38.5 | 34 | |
| 61–70 | 3,105 (24.7) | 39.0 | 34 | |
| 51–60 | 4,278 (34.1) | 39.1 | 34 | |
| 41–50 | 2,341 (18.7) | 39.9 | 33 | |
| ≤40 | 426 (3.4) | 43.1 | 35 | |
| Insurance type | <0.001 | |||
| Private insurance | 5,790 (46.2) | 36.6 | 32 | |
| Medicare | 4,500 (35.9) | 39.7 | 34 | |
| Medicaid | 1,110 (8.8) | 46.7 | 40 | |
| Not insured | 747 (6.0) | 42.2 | 35 | |
| Other/unknown | 399 (3.2) | 45.7 | 37 | |
| Median household income (dollars) in zip code of patient residence | <0.001 | |||
| ≥63,000 | 3,627 (28.9) | 37.6 | 33 | |
| 48,000–62,999 | 3,335 (26.6) | 38.6 | 33 | |
| 38,000–47,999 | 3,132 (25.0) | 39.8 | 34 | |
| <38,000 | 2,355 (18.8) | 41.9 | 35 | |
| Unknown | 97 (0.8) | 40.1 | 33 | |
| Education status (% without high school diploma) in zip code of patient residence | <0.001 | |||
| <7.0 | 2,993 (23.9) | 36.3 | 32 | |
| 7.0–12.9 | 4,096 (32.6) | 38.4 | 33 | |
| 13–20.9 | 3,348 (26.7) | 40.1 | 34 | |
| ≥21.0 | 2,017 (16.1) | 43.6 | 38 | |
| Unknown | 92 (0.7) | 40.7 | 33.5 | |
| Urban/rural category | <0.001 | |||
| Metropolitan ≥1 million | 6,409 (51.1) | 41.1 | 34 | |
| Metropolitan <1 million | 3,887 (31.0) | 36.9 | 33 | |
| Urban | 1,747 (13.9) | 37.8 | 34 | |
| Rural | 198 (1.6) | 38.9 | 33 | |
| Unknown | 305 (2.4) | 39.1 | 35 | |
| Distance to reporting center (miles) | <0.001 | |||
| ≤10 | 7,016 (55.9) | 38.9 | 33 | |
| 11–20 | 2,569 (20.5) | 38.8 | 34 | |
| 21–50 | 2,025 (16.1) | 38.9 | 34 | |
| >50 | 847 (6.8) | 43.5 | 39 | |
| Reporting facility type | <0.001 | |||
| Community | 1,287 (10.3) | 38.0 | 33 | |
| Comprehensive community | 5,528 (44.1) | 36.0 | 32 | |
| Academic | 3,996 (31.9) | 44.1 | 38 | |
| Integrated network | 1,385 (11.0) | 38.0 | 33 | |
| Unknown | 350 (2.8) | 44.8 | 35 | |
| Reporting facility anal cancer patient volume | <0.001 | |||
| Lower third of facilities | 996 (7.9) | 37.7 | 33 | |
| Middle third of facilities | 2,635 (21.0) | 37.4 | 32 | |
| Upper third of facilities | 8,915 (71.1) | 40.0 | 34 | |
| Reporting facility location | <0.001 | |||
| Northeast | 2,466 (19.7) | 42.3 | 38 | |
| South | 4,296 (34.2) | 38.7 | 33 | |
| Midwest | 3,288 (26.2) | 35.7 | 32 | |
| West | 2,146 (17.1) | 41.2 | 35 | |
| Unknown | 350 (2.8) | 44.8 | 35 | |
| Transition in care | <0.001 | |||
| No | 2,365 (18.9) | 37.7 | 33 | |
| Yes | 6,742 (53.7) | 41.6 | 35 | |
| Unknown | 3,439 (27.4) | 35.7 | 31 | |
| Radiation plan type | <0.001 | |||
| Non-IMRT, non-proton | 7,071 (56.4) | 38.0 | 33 | |
| IMRT, proton | 5,475 (43.6) | 40.9 | 35 | |
| Charlson/Deyo comorbidity score | <0.001 | |||
| 0 | 10,212 (81.4) | 38.7 | 34 | |
| 1 | 1,528 (12.2) | 39.2 | 34 | |
| 2 | 806 (6.4) | 46.1 | 38 | |
| Clinical tumor classification | <0.001 | |||
| T0/IS | 9 (0.1) | 37.1 | 28 | |
| T1 | 1,809 (14.4) | 43.2 | 36 | |
| T2 | 6,374 (50.8) | 38.4 | 33 | |
| T3 | 3,042 (24.2) | 37.6 | 33 | |
| T4 | 1,108 (8.8) | 40.7 | 34 | |
| Unknown | 204 (1.6) | 45.3 | 39 | |
| Clinical nodal classification | <0.001 | |||
| N0 | 7,861 (62.7) | 39.0 | 34 | |
| N1 | 1,528 (12.2) | 37.8 | 33 | |
| N2 | 1,739 (13.9) | 39.8 | 34 | |
| N3 | 1,231 (9.8) | 41.8 | 35 | |
| Unknown | 187 (1.5) | 38.2 | 32 | |
P values reported from Kruskal-Wallis test. UVA, univariable analysis; TTI, time to treatment initiation; AAPI, Asian-American and Pacific Islander; IMRT, intensity-modulated radiation therapy; IS, in situ.