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. 2018 Dec 3;8:569. doi: 10.3389/fonc.2018.00569

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Copyright © 2018 Ji, Rong, Luo, Li, Jiang, Weng, Chen, Zhang, Xie and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The aberrantly expressed mRNAs in HCC tissues. Aberrantly expressed miRNAs calculated by edgeR R. 3847 up-regulated and 1048 down-regulated miRNAs were found (A); Aberrantly expressed miRNAs calculated by DESeq R. 1290 up-regulated and 883 down-regulated miRNAs were found (B). Red dots indicate up-regulated miRNAs and green dots indicate down-regulated miRNAs. Black dots show the miRNAs expression with |log₂FC| < 1. The X-axis represents an adjusted FDR value and the Y-axis represents the log₂FC value. The volcano plot was generated by the ggplot2 package of R language. The intersection of up-regulated mRNAs obtained using edgeR R and DESeq R (C). The intersection of down-regulated mRNAs obtained using edgeR R and DESeq R (D).