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. 2018 Dec 3;9:2830. doi: 10.3389/fimmu.2018.02830

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Copyright © 2018 Hsiao, Chu, Wu, van den Biggelaar, Pabst, Hébert, Kuijpers, Scicluna, I, Chen, Liebscher, Hamann and Lin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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PMNs specifically express ADGRG3 (GPR97). (A) RNA sequencing data showing aGPCR expression in sorted cord blood (CB), bone marrow (BM), and peripheral blood (PB) cell populations, derived from Maiga et al. (25). Shown are aGPCR with reads per kilobase per million mapped reads (RPKM) >1.5. (B) Mass spectrometry data showing protein expression of the aGPCRs EMR1, EMR2, EMR3, CD97, GPR97, and GPR114 in granulocyte populations, including neutrophils, eosinophils, and basophils, derived from Rieckmann et al. (26). (C) Linked RNA sequencing and mass spectrometry data showing expression of the aGPCRs ADGRE3 (EMR3), ADGRE5 (CD97), and ADGRG3 (GPR97) in precursor and mature granulocytes. FPKM, fragments per kilobase per million mapped reads; LFQ, label-free quantification.