Table 3.
Subject characteristics MCI cohort
| MCI | Stable | Progression to AD |
|---|---|---|
| n, (%) | 220 (61%) | 143 (39%) |
| Age, years (SD) | 67.3 (6.5) | 69.3 (7.4)* |
| Females, n (%) | 144 (65) | 73 (51)* |
| Level of education, mean (SD)† | 5.1 (1.4) | 5.0 (1.4) |
| APOE ε4 allele carriers, n (%) | 93 (42%) | 87 (61%) |
| MMSE score, mean (SD) | 27 (2.3) | 26 (2.8) |
| CSF Aβ1-42 (SD), pg/ml | 934 (299) | 679 (122)* |
| CSF tau (SD), pg/ml | 375 (227) | 668 (350)* |
| CSF Ptau (SD), pg/ml | 58 (29) | 70 (34)* |
| Follow-up duration, years (SD) | 2.5 (1.6) | 2.4 (1.3) |
Abbreviations: MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination; APOE, apolipoprotein E; Aβ42, amyloid β 1-42; Ptau, tau phosphorylated at threonine 181; SD, standard deviation; CSF, cerebrospinal fluid.
Data are mean (SD), unless otherwise specified. Independent T-test, Kruskal-Wallis test, or chi square test was used when applicable. *P < .05.
†
According to the Verhage system.