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GTN and chemodrug concentrations in combination treatments and the combination index (CI) used to determine the synergistic combination effects calculated using CompuSyn Software.
| Goniothalamin (GTN) ( μ M) | Combination Index (CI) | |||||
|---|---|---|---|---|---|---|
| 6.25 | 6.25 | 6.25 | 6.25 | 6.25 | ||
| Paclitaxel (PTX), ( μ M) | 0.125 | 0.0709 | ||||
|
| ||||||
| Vinblastine (VBT), ( μ M) | 1.25 | 0.18271 | ||||
|
| ||||||
| 5-Fluorouracil (5FU), ( μ M) | 10 | 0.80856 | ||||
|
| ||||||
| Cyclophosphamide (CPP), ( μ M) | 100 | 0.63287 | ||||
|
| ||||||
| Methotrexate (MTX), ( μ M) | 20 | 0.93235 | ||||
