TABLE 2.
Histopathological diagnosis | GBM, grade WHO IV | |
---|---|---|
Number of cases | 83 | |
Mean age (Year) | 50 (min ± 12.8 8, max 71) | |
Male | 50 (60%) | |
Gender | ||
Female | 33 (40%) | |
Karnofsky performance status ≥ 80 | 83 | |
radiotherapy after first surgery | 83/83 (100%) | |
chemotherapy after first surgery | 54/83 (65%) | |
Adjuvant treatment | ||
radiotherapy after second surgery | 15/83 (18%) | |
chemotherapy after second surgery | 47/83 (56%) | |
MGMT (tested methylated in a subset of patients treated with TMZ) | Primary GBM | 38/47 (81%) |
Recurrent GBM | 46/47 (98%) | |
Time to recurrence (months) | 0.84–67.30 | |
Survival after second surgery (months) | 0.03–25.75 | |
Overall survival (months) | 0.84–70.48 |
MGMT = methyl guanine methyl transferase; TMZ = temozolamide