Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 3;9:1382. doi: 10.3389/fphar.2018.01382

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Ðanić, Stanimirov, Pavlović, Goločorbin-Kon, Al-Salami, Stankov and Mikov.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Receptor-dependent and receptor-independent regulation of metabolic and signaling pathways by bile acids in metabolic syndrome. The effects of bile acid-activated receptors FXR and TGR5 on glucose, lipid and energy metabolism as well as on vascular events associated with atherosclerosis. FXR and TGR5 have significant number of currently identified overlapping effects. On the other hand, the effects of UDCA are not associated with activation of these bile acid receptors, instead UDCA exerts various physiological/pharmacological effects which are associated with its specific structural properties.