Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Dec 3;9:1402. doi: 10.3389/fphar.2018.01402

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2018 Kameyama, Ohuchi, Funato, Ando, Inagaki, Sato, Seki, Kawase, Tsuruma, Nishino, Nakamura, Shimazawa, Saito, Takeda, Kaneko and Hara.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Efficacy of prednisolone in reversing DMD pathology. (A) Immunostaining using skeletal muscle marker (myosin heavy chain, MHC), and apoptosis marker (cleaved caspase-3, Cas). Prednisolone (PDN) restored decreased MHC area and increased apoptosis cells. Scale bars = 100 μm. (B) Quantification of the MHC area of myotubes from control individual, non-treated myotubes from DMD (NT), and prednisolone-treated myotubes from DMD (PDN). Data are shown as means ± SEM (n = 4). (C) Western blot analysis of cleaved caspase-3 in control individual (Ctrl), NT, and PDN. Data are shown as means ± SEM (n = 5). ^#p < 0.05 vs. Ctrl and ^∗p < 0.05 vs. NT (Student’s t-test), ^∗p < 0.05 vs. NT (Student’s t-test).