The coefficients obtained using multivariate linear regression on a combined response of four fluorescence variables represented by NFT (normalized fluorescence in tumor), NFM (normalized fluorescence in muscle), NFL (normalized fluorescence in liver) and NFK (normalized fluorescence in kidney), and two categorical predictors represented by Time (2, 4 and 24 hours) and pHLIP® variants (Var3, Var7, and WT). All coefficients marked by bold color indicate significant difference from the corresponding reference level. The intercept values correspond to the averages of four fluorescence variables at the reference levels of the predictors: Time = 2 hours and pHLIP® variant = Var3.