Table 4.

Characteristics and measured outcomes of randomized controlled trials for peripheral neuropathy or neuropathic pain in pediatric oncology patients

NCT Number	Intervention	Diagnoses	Chemotherapy	Ages	Measured Outcomes
NCT01506453	Gabapentin	Acute lymphoblastic leukemia	Vincristine	1-18 years	- daily total dose of oral morphine (mg/kg/day) - current pain score - pain score in previous 24 hours -
NCT00369564	Glutamic acid	Wilms tumor Rhabdomyosarcoma ALL Non-Hodgkin lymphoma	Vincristine	3-20 years	- Neurotoxicity - Frequency and type of neurotoxicity - Ability to receive all scheduled doses of vincristine
NCT00365768	Glutamine	Leukemia Solid tumors Medulloblastoma	Vincristine	5-21 years	- Incidence of vincristine-induced peripheral neuropathy - Number of participants with progression of neuropathy
NCT00112996	Alpha-Lipoic Acid	Solid tumors	Cisplatin Oxaliplatin	Any	- Severity of neuropathy - Group differences in change scores - Number of courses received - Optimal tumor response