Figure 5.

Associations between intrapair differences in insulin-based indices and the AUC values of metabolites in all 64 monozygotic twin pairs. Intrapair differences were calculated by subtracting the measurement of the cotwin with lower BMI from the measurement of the cotwin with higher BMI. Indices and AUC values were rank-normalized prior to analysis while adjusting for sex and age, and Pearson correlation coefficients were estimated. Color denotes the strength of correlations (red = positive, blue = negative) and asterisks mark their significance (*P < 0.0025; **P < 0.0005; ***P < 0.00005). IDL, intermediate-density lipoprotein.