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. 2018 Dec 5;12:4139–4147. doi: 10.2147/DDDT.S186614

Table 2.

Inhibitory activity of compounds against PTP1B and SHP2 phosphatases

Tested compounds IC50 against PTP1B IC50 against SHP2
Asp-Phe 52.6±3.7 µM 108.7±16.9 µM
Phe-Asp 52.1±1.4 µM 5.2±0.4 µM
Phe-Phe-Asp 104.2±15.9 µM 113.6±23.6 µM
Phe-Asp-Phe 255.1±29.4 µM 97.9±17.9 µM

Note: Values are expressed as IC50 ± SD.