Table 1.
General characteristics of studies included in the meta-analysis
| Study (first author, year) | Region | Study type | No of patients
|
Age (years), mean ± SD ET OT
|
Gender, M/F
|
Extent of thyroidectomy, TT/LTT
|
Surgical approach | Matchinga | Quality score | ||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| ET | OT | ET | OT | ET | OT | ET | OT | ||||||
|
| |||||||||||||
| Chung 200726 | Korea | RS | 103 | 198 | 38.2±8.2 | 47.2±10.2 | 1/102 | 25/173 | 88/15 | 172/26 | BABA | 4, 9 | 6 |
| Hong 201127 | Korea | RS | 57 | 60 | 39.60±7.88 | 41.77±9.61 | 6/51 | 11/49 | 0/57 | 0/60 | BABA/UABA | 1, 2, 4, 7, 9 | 7 |
| Kim 201128 | Korea | RS | 95 | 138 | 39.9±9.1 | 51.8±8.9 | 2/93 | 34/104 | 95/0 | 138/0 | BABA | 9 | 6 |
| Tae 201129 | Korea | RS | 31 | 36 | 36.2±9.9 | 44.6±11.8 | 1/30 | 11/25 | 3/28 | 0/36 | UABA/TAA | 4–9 | 7 |
| Lee 201230 | Korea | RS | 37 | 41 | 42.3±7.6 | 49.0±10.8 | 0/37 | 3/38 | 0/37 | 0/41 | TAA | 2, 4, 5, 7–9 | 7 |
| Tan 201531 | China | RS | 34 | 30 | 30 (16–44)b | 43 (25–76)b | 2/32 | 4/26 | 0/34 | 0/30 | BBA | 2, 4, 9 | 7 |
| Huang 20167 | China | RS | 75 | 123 | 37.8±10.6 | 39.2±11.3 | 16/59 | 31/92 | 75/0 | 123/0 | TAA | 1–5, 7–9 | 7 |
| Kim 201632 | Korea | RS | 173 | 830 | 38.90 (17–57)b | 49.53 (17–84)b | 13/160 | 96/734 | 56/117 | 684/146 | BABA | 2 | 5 |
| Lee 201633 | Korea | RS | 75 | 233 | 42.2±8.6 | 52.1±9.3 | 3/72 | 15/218 | 0/75 | 0/233 | BABA/UABA | 2, 4, 5, 7, 9 | 6 |
| Park 201634 | Korea | RS | 50 | 102 | 38.0±9.4 | 50.8±11.5 | 4/46 | 14/88 | 50/0 | 102/0 | UABA | 2, 4–7, 9 | 5 |
| Xiang 201635 | China | RS | 49 | 47 | 34.2±7.0 | 46.9±13.3 | 0/49 | 6/41 | 49/0 | 47/0 | BBA | 7, 9 | 6 |
| Ren 201736 | China | RS | 20 | 35 | 36.05±7.536 | 36.06±5.646 | 0/20 | 0/35 | 0/20 | 0/35 | BBA | 1–3, 9 | 6 |
Notes:
a
Features matching ET and OT: 1 = age; 2 = gender; 3 = body mass index; 4 = tumor size; 5 = multiplicity; 6 = bilaterality; 7 = extrathyroidal extension; 8 = tumor stage; 9 = extent of thyroidectomy.
b
Median (range).
Abbreviations: BABA, bilateral axillobreast approach; BBA, bilateral breast approach; ET, endoscopic thyroidectomy; F, female; LTT, less than total thyroidectomy; M, male; OT, open thyroidectomy; RS, retrospective study; TAA, transaxillary approach; TT, total thyroidectomy; UABA, unilateral axillobreast approach.