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. 2018 Dec 5;14:2349–2361. doi: 10.2147/TCRM.S183612

Table 4.

Meta-analysis of the subgroups according to the extent of thyroidectomy

Outcomes No of studies No of patients
OR/WMD 95% CI P-value I2 (%)
ET OT

TT
 Operative time 4 269 410 47.40 34.18, 60.61 <0.00001 84
 No of retrieved LNs 4 269 410 −0.10 −0.50, 0.30 0.63 0
 Blood loss 2 125 225 2.35 −7.27, 11.97 0.63 79
 Volume of drainage 2 145 240 100.31 −33.67, 234.29 0.14 94
 Hospitalization period 2 145 240 0.33 0.10, 0.56 0.005 0
 Transient RLN palsy 4 269 410 1.58 0.66, 3.79 0.31 0
 Permanent RLN palsy 3 194 287 1.89 0.49, 7.33 0.36 20
 Transient hypocalcemia 3 194 287 1.48 0.68, 3.20 0.32 70
 Permanent hypocalcemia 3 194 287 1.35 0.46, 3.99 0.58 0
 Hematoma or bleeding 3 219 308 2.93 0.61, 14.02 0.18 0
 Seroma 2 170 261 0.67 0.10, 4.55 0.68 0
LTT
 Operative time 4 148 166 45.96 29.33, 62.59 <0.00001 90
 No of retrieved  LNs 4 203 364 −0.89 −2.48, 0.70 0.27 90
 Blood loss 2 54 65 6.52 −0.72, 13.76 0.08 46
 Duration of drainage 2 54 65 2.20 1.82, 2.59 <0.00001 0
 Volume of drainage 2 54 65 114.99 99.74, 130.24 <0.00001 0
 Hospitalization period 3 114 136 0.81 −0.19, 1.82 0.11 95
 Transient RLN palsy 4 186 358 2.83 1.26, 6.36 0.01 44
 Permanent RLN palsy 3 152 328 5.29 0.54, 52.22 0.15 0
 Transient hypocalcemia 2 54 65 0.31 0.07, 1.36 0.12 0
 Hematoma or bleeding 4 148 166 2.20 0.62, 7.84 0.22 0

Abbreviations: ET, endoscopic thyroidectomy; LN, lymph node; LTT, less than total thyroidectomy; OT, open thyroidectomy; RLN, recurrent laryngeal nerve; TT, total thyroidectomy; WMD, weighted mean difference.