Table 2.
Correlation Between BRAFT1799A Gene Mutation and IHC Positivity for the Mutant Protein in PTCs According to Tumor Subtype
| Genotype Intensity | IHC Staining | |||
|---|---|---|---|---|
| 0 | 1+ | 2+ | 3+ | |
| Classic PTC BRAF-T1799A (n = 11) | 0 | 0 | 0 | 11 (100) |
| Classic PTC BRAF-wt (n = 5) | 4 (80) | 1 (20) | 0 | 0 |
| TCV PTC BRAF-T1799A (n = 2) | 0 | 0 | 0 | 2 (100) |
| FVPTC BRAF-wt (n = 9; 2 Inf and 7 Enc) | 4 (44) | 5 (56) | 0 | 0 |
| Micro PTC BRAF-T1799A (n = 3) | 0 | 0 | 0 | 3 (100) |
| Micro PTC BRAF-wt (n = 1) | 0 | 1 (100) | 0 | 0 |
Abbreviations: Enc, encapsulated; FVPTC, follicular variant of PTC; Inc, infiltrative; Micro PTC, PTC microcarcinoma variant; TCV, tall cell variant. Data are n (%).