TABLE 1.

Structures of diadenylate cyclases and phosphodiesterases and their domains

PDB ID	Enzyme	Domain(s) or mutation(s)	Ligand(s)	Metal ion	Reference
3C1Z	DisA	DAC	None	None	5
3C23	DisA	DAC	3′-dATP	None	5
4YVZ	DisA	DAC	3′-dATP	Mn2+	50
3C1Y	DisA	DAC	c-di-AMP	None	5
4YXJ	DisA	DAC	ApCpp	None	50
4RV7	CdaA	DAC	ATP	Mg2+	43
2FB5	CdaS	DAC	None	None	Unpublished data a
2M1C	GdpP	PAS	None	None	82
5XSI	GdpP	DHH-DHHA1	None	Mn2+	107
5XSN	GdpP	DHH-DHHA1	c-di-AMP	Mn2+	107
5XSP	GdpP	DHH-DHHA1	5′-pApA	Mn2+	107
5XT3	GdpP	DHH-DHHA1	c-di-GMP	Mn2+	107
5JJU	DhhP	DHH-DHHA1	5′-pApA and 5′-AMP	Mn2+	93
5O25	DhhP	DHH-DHHA1	None	Mn2+	89
5O58	DhhP	DHH-DHHA1	5′-pApG	Mn2+	89
		D80N, D154N
5O70	DhhP	DHH-DHHA1	5′-AMP	Mn2+	89
		D80N, D154N
5O1U	DhhP	DHH-DHHA1	5′-AMP	Mn2+	89
5O4Z	DhhP	DHH-DHHA1	5′-AMP	Mn2+	89
		D80N, D154N
5O7F	DhhP	DHH-DHHA1	5′-GMP	Mn2+	89
4S1B	PgpH	HD	c-di-AMP	Fe3+	96
4S1C	PgpH	HD	None	Fe3+	96

^aR. Zhang, M. Zhou, S. Ginell, J. Abdullah, F. Collart, and A. Joachimiak.