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. 2018 Dec 3;9:1396. doi: 10.3389/fphar.2018.01396

Table 2.

Total expenditure for the top five classes of antibiotics based on ACT-4 at different levels of healthcare institutions in Shandong, 2012–2016 (million US$).

Institutions 2012 2013 2014 2015 2016
ATC Expenditure ATC Expenditure ATC Expenditure ATC Expenditure ATC Expenditure
Tertiary hospital J01DC 234.7 J01DD 233.2 J01DD 297.5 J01DD 386.2 J01DD 397.6
J01DD 231.6 J01DC 184.1 J01DC 245.8 J01DC 268.1 J01DH 319.4
J01MA 126.8 J01MA 147.1 J01MA 191.7 J01DH 234.6 J01DC 266.5
J01DB 117.9 J01CR 130.1 J01CR 147.1 J01CR 234.4 J01CR 257.2
J01CR 102.6 J01DB 105.5 J01DH 139.4 J01MA 233.6 J01MA 234.8
Secondary hospital J01DD 211.9 J01DD 205.1 J01DD 226.8 J01CR 322.8 J01CR 353.7
J01DC 168.6 J01DC 168.1 J01DC 223.5 J01DD 301.0 J01DD 317.5
J01CR 139.3 J01CR 146.7 J01CR 208.5 J01DC 277.6 J01DC 255.7
J01DF 114.2 J01DB 101.4 J01CA 133.4 J01CA 192.4 J01CA 189.3
J01DB 104.9 J01CA 94.1 J01DB 117.9 J01DB 135.8 J01DB 142.8
Rural PHC J01DD 110.2 J01DD 128.3 J01CR 161.9 J01CR 156.5 J01CR 146.3
J01FA 84.9 J01FA 107.4 J01DC 137.1 J01DC 142.2 J01DC 131.8
J01DC 79.1 J01DC 95.9 J01DD 109.4 J01DD 103.1 J01DD 95.5
J01CR 79.0 J01CR 93.6 J01FA 109.0 J01FF 92.6 J01FF 80.7
J01CE 58.7 J01DB 69.8 J01MA 78.4 J01FA 83.6 J01FA 77.8
Urban PHC J01DD 10.1 J01DD 12.2 J01DC 17.0 J01DC 19.0 J01DC 26.3
J01DC 9.4 J01FA 12.1 J01CR 13.5 J01CR 15.7 J01CR 24.1
J01FA 9.0 J01DC 11.7 J01FA 13.0 J01MA 12.2 J01FA 17.5
J01CR 7.2 J01CR 10.2 J01MA 11.2 J01DD 12.0 J01DD 16.0
J01DB 5.5 J01CE 5.7 J01DD 10.7 J01FA 11.7 J01MA 16.0

Based on the average exchange rate in 2016, 1 US$, 6.64 RMB. ATC-4, the 4th level of ATC which is classified according to chemical subgroup; PHC, Primary healthcare center. J01CA, Penicillin with an extended spectrum; J01CE, Beta-lactamase sensitive penicillin; J01CR, Combinations of penicillin, incl. beta-lactamase inhibitors, J01DB, First-generation cephalosporins, J01DC, Second-generation cephalosporins; J01DD, Third-generation cephalosporins; J01DF, Monobactams; J01DH, Carbapenems, J01FA, Macrolides; J01FF, Lincosamides; J01MA, Fluoroquinolones.