Figure 4.

The role of the ERK1/2 pathway in the regulation of cell proliferation by SVNs and SV.
Notes: The results are the mean values of three independent measurements (±SD). *P<0.05 vs BCG; #P<0.05 SVNG vs SVG; ▲P<0.05 drug vs drug + PD98059; ♦P<0.05 vs BCG + PD98059; ∆P<0.05 SVNG + PD98059 vs SVG + PD98059.
Abbreviations: BCG, blank control group; DFNG, drug-free nanomicelles group; SD, standard deviation; SV, simvastatin; SVG, simvastatin group; SVNs, simvastatin-loaded nanomicelles; SVNG, simvastatin-loaded nanomicelles group.