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. 2018 Dec 5;13:8165–8178. doi: 10.2147/IJN.S182998

Figure 5.

Figure 5

The role of the ERK1/2 pathway in the regulation of the cell cycle by SVNs and SV.

Notes: The results are the mean values of three independent measurements (±SD). *P<0.05 vs BCG; #P<0.05 SVNG vs SVG; P<0.05 drug vs drug + PD98059; P<0.05 vs BCG + PD98059; P<0.05 vs SVG + PD98059.

Abbreviations: BCG, blank control group; DFNG, drug-free nanomicelles group; SD, standard deviation; SV, simvastatin; SVG, simvastatin group; SVNs, simvastatin-loaded nanomicelles; SVNG, simvastatin-loaded nanomicelles group.