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The role of the ERK1/2 pathway in the regulation of cell apoptosis by SVNs and SV. The results are the mean values of three independent measurements (±SD). ▲P<0.05 drug vs drug + PD98059; ♦P<0.05 vs BCG + PD98059.
Abbreviations: BCG, blank control group; DFNG, drug-free nanomicelles group; SD, standard deviation; SV, simvastatin; SVG, simvastatin group; SVNs, simvastatin-loaded nanomicelles; SVNG, simvastatin-loaded nanomicelles group.
