Table 7.

CsA-loaded mPEG-PLA micelles release in vitro

Model	CsA micelles
	Equation	R2	R2adjusted
Zero-order	Q=1.252t	0.8197	0.8197
First-order	Q=100 [1−exp(−0.03t)]	0.9851	0.9851
Higuchi	Q=10.020t0.5	0.9378	0.9378
Hixson–Crowell	Q=100 [1−(1−0.008*t)3]	0.9818	0.9817
Weibull	Q=100 {1−exp[−((t+0.896)1.183)/65.155]}	0.9879	0.9849
Peppas–Sahlin	Q=2.419t1.005−0.016t2.01	0.9917	0.9916
Korsmeyer–Peppas	Q=7.2t0.584	0.9475	0.9417

Abbreviations: CsA, cyclosporine-A; mPEG, methoxy poly(ethylene glycol); PLA, poly(lactide).